For research use only. Not for human consumption.
Ipamorelin is a synthetic pentapeptide and selective growth hormone-releasing peptide (GHRP) that stimulates growth hormone secretion with minimal effects on cortisol or prolactin, used in research on endocrine signaling, tissue repair, and metabolic regulation.
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$50.00
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4 in stock
Ipamorelin is a synthetic pentapeptide (five amino acids) that functions as a selective growth hormone-releasing peptide (GHRP). It binds to the ghrelin receptor (GHS-R1a) in the pituitary gland, stimulating the release of growth hormone (GH) without significantly affecting cortisol or prolactin.
Peptide Sequence: Aib-His-D-2-Nal-D-Phe-Lys
Molecular Weight: ~711.9 Da
Stability: Water-soluble, short half-life, used in vitro or in vivo experimental models
Selectivity: Specifically promotes GH release, minimizing side effects
Research on growth hormone signaling and endocrine regulation
Studying muscle growth, tissue repair, and bone regeneration
Investigating IGF-1 mediated pathways
Evaluating metabolic and anti-aging effects
Ipamorelin is a highly selective GH-releasing peptide that enables controlled experimental studies of growth hormone secretion, tissue regeneration, and metabolic processes, widely used in preclinical and laboratory research.
Type: Synthetic pentapeptide (5 amino acids)
Amino Acid Sequence: Aib-His-D-2-Nal-D-Phe-Lys
Molecular Weight: ~711.9 Da
Structure: Linear peptide with modifications (Aib = α-aminoisobutyric acid) to enhance stability
Receptor Target: Ghrelin receptor (GHS-R1a)
Selective GH Release: Binds to pituitary GHS-R1a receptor to stimulate growth hormone secretion
Minimal Side Effects: Does not significantly increase cortisol, prolactin, or appetite hormones
Signal Pathways Activated:
Ghrelin-GHSR1a signaling
GH-IGF-1 axis
Downstream PI3K/Akt and MAPK pathways for growth and proliferation
Muscle and Tissue Growth: Promotes protein synthesis, tissue repair, and regeneration
Metabolic Regulation: Influences lipid metabolism and IGF-1 production
Anti-Apoptotic Effects: Supports cell survival under stress conditions
Water Soluble: Easily dissolved in sterile water or buffers for experimental use
Half-Life: Short in vivo; designed for controlled GH stimulation in research
Handling Sensitivity: Sensitive to heat, pH extremes, and repeated freeze-thaw cycles
Ipamorelin is a synthetic, selective GH-releasing pentapeptide with high receptor specificity, minimal hormonal side effects, and activation of growth hormone and IGF-1 signaling pathways. Its biochemical profile makes it suitable for experimental research in growth, tissue regeneration, metabolic regulation, and endocrine studies.
Investigating pituitary GH release mechanisms via GHS-R1a receptor
Studying the GH-IGF-1 axis in cell culture and animal models
Exploring dose-response effects on growth hormone secretion
Research on skeletal muscle hypertrophy and repair
Studying tendon, cartilage, and bone regeneration
Evaluating satellite cell proliferation and differentiation in tissue repair models
Studying lipid metabolism and glucose uptake regulation
Investigating IGF-1 mediated signaling downstream of GH release
Assessing endocrine modulation without affecting cortisol or prolactin
Research on cellular regeneration and anti-apoptotic pathways
Investigating tissue repair and rejuvenation models
Evaluating synergistic effects with other GH-releasing peptides or analogs
Ipamorelin is used in research to study growth hormone secretion, tissue regeneration, metabolic regulation, and endocrine signaling. Its high selectivity and minimal side effects make it ideal for preclinical, in vitro, and animal studies exploring GH-related biology.
Tested by Freedom Diagnostics @ Freedom Diagnostics Testing – Reliable. Accountable. Accessible.
Temperature: Store refrigerated at 2–8 °C (36–46 °F) for short-term use
Long-Term Storage: Freeze at −20 °C or below to maintain stability
Light Protection: Keep protected from direct light
Moisture Protection: Keep in original sealed vial
Shelf Life: Typically 12–24 months when stored properly
Diluent: Sterile water or bacteriostatic water
Temperature: Refrigerate at 2–8 °C
Use Period: Recommended within 7–14 days
Handling: Gently swirl to mix; avoid vigorous shaking
Do NOT freeze after reconstitution
Inspect solution before use: should be clear, colorless, and free of particulates
Discard if cloudy, discolored, or precipitated
Use sterile technique during reconstitution and experimental handling
Protect from heat, light, and mechanical agitation to preserve peptide integrity
Ipamorelin is most stable as a lyophilized powder stored refrigerated or frozen. Once reconstituted, it should be kept cold, used promptly, and protected from light and agitation to maintain biological activity for laboratory and research use.
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