MT-2 (Melanotan-2) is a synthetic α-MSH analog that stimulates melanin production, skin tanning, and photoprotection, while also influencing sexual function and melanocortin-mediated metabolic pathways in research studies.
For research use only. Not for human consumption.
MT-2 (Melanotan-2) is a synthetic α-MSH analog that stimulates melanin production, skin tanning, and photoprotection, while also influencing sexual function and melanocortin-mediated metabolic pathways in research studies.
Price:
$40.00
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4 in stock
MT-2 is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH) designed to activate multiple melanocortin receptors (MC1R–MC5R). While its primary effect is to stimulate melanin production and skin pigmentation, MT-2 also affects sexual function, energy metabolism, and appetite regulation through central melanocortin pathways. Chemically modified for stability and enzymatic resistance, MT-2 is suitable for preclinical and laboratory research in pigmentation, melanocortin receptor signaling, sexual physiology, and metabolic studies.
Peptide Length: 7–13 amino acids (commonly 13)
Structure: Linear peptide with chemical modifications for stability and receptor specificity
Mechanism: Activates MC1R for melanogenesis and MC3R–MC5R for metabolic and sexual effects
Water-Soluble: Suitable for in vitro and preclinical studies
Studying skin pigmentation and melanin synthesis pathways
Investigating sexual function and erectile physiology via MC4R signaling
Researching energy balance, appetite regulation, and melanocortin receptor activity
Evaluating photoprotective mechanisms in skin cells
MT-2 is a multi-receptor α-MSH analog that promotes skin tanning, photoprotection, sexual function, and metabolic regulation. Its chemical stability and receptor versatility make it a valuable tool for research on pigmentation biology, melanocortin signaling, and preclinical metabolic or sexual physiology studies.
Type: Synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH)
Amino Acid Length: 7–13 amino acids (commonly 13 in most research formulations)
Molecular Weight: ~1025–1660 Da depending on sequence
Structure: Linear peptide with chemical modifications to enhance stability and receptor binding
Receptor Targets: Primarily MC1R (melanogenesis), also MC3R–MC5R (sexual function, metabolism, energy balance)
Melanogenesis Activation: Stimulates cAMP signaling in melanocytes, increasing melanin synthesis
Sexual Function Modulation: Activates MC4R and related receptors in CNS pathways controlling libido and erectile function
Metabolic Effects: Influences energy homeostasis, appetite, and metabolic signaling via melanocortin receptor pathways
Stability Modifications: Resistant to enzymatic degradation to prolong activity compared to natural α-MSH
Skin Pigmentation: Induces tanning and photoprotection
UV Protection: Enhances melanin-mediated defense against UV damage
Sexual Physiology: Modulates libido, sexual arousal, and erectile function
Metabolic Regulation: Impacts appetite, energy expenditure, and melanocortin-mediated metabolic pathways
Water-Soluble: Suitable for in vitro studies and preclinical research
Linear Structure: Facilitates cellular uptake and receptor interactions
Stability: Enhanced half-life and enzymatic resistance compared to α-MSH
MT-2 is a synthetic, multi-receptor α-MSH analog with linear structure, water solubility, and chemical modifications that allow it to regulate melanin production, sexual function, and melanocortin-mediated metabolic pathways. Its biochemical properties make it ideal for preclinical and laboratory research on pigmentation, photoprotection, and CNS-regulated metabolic and sexual physiology.
Investigating melanin synthesis pathways in melanocytes
Studying skin tanning independent of UV exposure
Evaluating photoprotective mechanisms against UV-induced damage
Researching pigmentation disorders (e.g., vitiligo, hypopigmentation)
Studying libido, sexual arousal, and erectile physiology via MC4R activation
Researching central melanocortin signaling in sexual behavior
Exploring therapeutic potential for sexual dysfunction in preclinical models
Examining appetite modulation and energy homeostasis through MC3R–MC5R
Investigating melanocortin receptor-mediated metabolic pathways
Researching effects on weight management and obesity models
Evaluating MC1R–MC5R receptor binding and signaling
Investigating peptide-receptor interactions and structure-activity relationships
Studying multi-receptor effects of synthetic melanocortin analogs
MT-2 is widely used in research to study skin pigmentation, photoprotection, sexual function, and melanocortin receptor-mediated metabolism. Its multi-receptor activity and chemical stability make it a versatile tool for preclinical and laboratory studies in dermatology, endocrinology, and reproductive physiology.
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Temperature: Store refrigerated at 2–8 °C (36–46 °F) for short-term use
Long-Term Storage: Freeze at −20 °C or lower to maintain stability
Light Protection: Keep protected from direct light
Moisture Protection: Keep the vial sealed and dry
Shelf Life: Typically 12–24 months when stored properly
Diluent: Sterile water or bacteriostatic water
Temperature: Store refrigerated at 2–8 °C
Use Period: Recommended within 7–14 days
Handling: Gently swirl to dissolve; avoid vigorous shaking
Do NOT freeze after reconstitution
Inspect solution before use: should be clear, colorless, and free of particulates
Discard if cloudy, discolored, or precipitated
Use sterile technique during reconstitution and handling
Protect from heat, light, and mechanical agitation to maintain peptide integrity
MT-2 is most stable as a lyophilized powder stored refrigerated or frozen. Once reconstituted, it should be kept cold, used promptly, and protected from light and agitation to preserve biological activity for laboratory and preclinical research.
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